Improvement of sticking tendency of granules during tabletting …
Semantic Scholar extracted view of "Improvement of sticking tendency of granules during tabletting process by pressure swing granulation" by N. F. A. Bakar et al.
Mechanical properties of powders for compaction and tableting…
How could an understanding of these properties help alleviate, or predict, challenges encountered with high-speed presses upon large-scale manufacturing, such as loss of crushing strength, sticking, picking, capping and lamination?
Getting it Right
Tablet sticking is often considered the most frequent and challenging problem within tablet manufacturing. Sticking is characterised by a build-up of granule on the punch tip face, causing tablets to be left with an altered and undesirable appearance and, more importantly, a variation in weight. The first recourse is the removal of the tablet tooling from …
Using the well plan™ software model to determine the …
Also, in this well, mechanical pipe sticking occurs due to the actual flow rate needed to achieve the best hole cleaning being less than the minimum flow rate that was computed utilizing well Plan™ software.
A material sparing method for quantitatively measuring tablet sticking …
The aim of this study was to develop a material-sparing method to quantitatively measure sticking during tablet manufacturing and to allow direct comparison of blends in terms of sticking.
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doi:10.1016/j.powtec.2007.02.037
A novel binderless coating method was developed to eliminate the sticking problem during tabletting process for the granules of a drug powder of high stickiness by using Pressure Swing Granulation ...
Why is Good Tablet Design so Important and How to …
Good tablet design is extremely important. It has an impact on anti-counterfeiting, tooling strength, tablet coating, durability and functionality. It also helps to avoid downstream manufacturing problems such as tablet sticking, picking, lamination, capping and premature tooling failures.
(PDF) Enhancing Flow Properties and Preventing Sticking and Picking …
The potential of StarTab® in enhancing flow properties and addressing sticking issues in pharmaceutical applications is highlighted.
Tabletting equipment: common problems and how to avoid …
Good quality: to produce highquality tablets, the equipment in the tablet making process should be of high quality, especially the tablet tooling because this is a mirror image of the tablet. Many production problems such as picking, sticking and capping can be eliminated by using superior tooling.
Considerations To Alleviate Sticking And Picking …
The design process for an oral solid dosage form overlooks some of the seemingly minor details of tablet design. In this article, explore how compression tooling manufacturers can identify potential sticking and …
15 Common Tablet Problems and How to Address Them
Picking is a specific type of sticking. It occurs when the tablet material is left behind on the punch faces with embossing designs. Picking can result in tablet surface damage, incomplete tablets, or weight and appearance variations.
Good Tablet Design: Enhancing Pharmaceutical Formulations
Good tablet design helps to avoid downstream manufacturing problems such as tablet sticking, picking, lamination, capping and premature tooling failures. It is essential to consider these at the beginning of the process, ensuring a problem free, high quality, end product, so getting all these factors right is imperative to a 'good' tablet ...
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British Journal of Pharmacy
In this study, the application of directly compressible starch (StarTab®) as a multifunctional excipient to improve flow, tablet compressibility, and prevent sticking and picking
Predictive Model Increases Novartis' Tablet Production by …
The company's Italian division implemented new tooling coating and design to stop downtime caused by sticking and picking in tablet manufacturing operations.
Improvement of sticking tendency of granules during tabletting …
Overall, PSG technique was found to be successful in eliminating sticking tendency of tablets during the tabletting process and the tablet hardness produced from the coated granules was found to be sufficiently strong enough to withstand handling and packaging process in the pharmaceutical industries.
Newly developed surface modification punches treated with …
Sticking is a serious problem during the manufacturing process of tablets. In order to prevent this, we used alloying techniques to prepare metal hardening (MH) and electron beam processing infinite product (EIP) punches with rougher asperity of surfaces than a hard chrome plated (HCr) punch. This s …
8 Types of Tablet Defects
Tablet defects. Tablet defects related to the tabletting process. Capping and Lamination. Tablet defects related to excipients. Chipping; Sticking; Picking and Binding. Tablet defects related to more …
Predicting lubricants effect on tablet sticking using …
The most widely seen tablet manufacturing issues are capping, lamination, picking, and sticking (Han et al., 2008). These problems can result in batch failures, production delays, and an increase in time to market.
Reformulation of Tablets to Resolve Sticking Picking Issue Faced …
Results: The tablets of potassium-salt of compound-XY showed sticking picking problem during tablet compression. In order to resolve the issue, formulation composition of these tablets was studied.
Evaluating the effect of glidants on tablet sticking …
Tablet manufacturing has faced common issues such as capping, laminating, picking and sticking since the invention of tablet technology. Several topics have emerged in the research and development and manufacturing environment while sticking is becoming a more prominent concern among drug makers.
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Tabletting
Tablet defects bedevil many manufacturers. This article outlines some strategies that tablet production experts use to resolve the most common ones, including weight variation, black spots, capping, and sticking and picking.
Common Tablet Defects: Causes and Remedies
Picking happens when a part of the tablet gets sticks to the punch surface and gets eroded from the tablet surface. It is a more specific term that describes product sticking within the letters, logos, or designs on the punch faces.
farmafix.com
Doctor Helps solve tabletting problems Sticking, Picking and Corrosion are some of the most common problems faced in Tablet Production. These problems have increased due to Direct Compression and Complex Formulation. To reduce such issues we offer tooling with special plating.
Sticking and Picking in Pharmaceutical Tablet Compression: An IQ
Sticking and picking during tablet manufacture has received increasing interest recently, as it causes tablet defects, downtime in manufacturing and yield losses.
Improvement of sticking tendency of granules during tabletting …
Overall, PSG technique was found to be successful in eliminating sticking tendency of tablets during the tabletting process and the tablet hardness produced from the coated granules was found to ...